Alterations in checkpoint and DNA repair pathways Resines UV may provide adaptive mechanisms contributing to acquired drug resistance.Here, we investigated the levels of proteins mediating DNA damage signaling and -repair in RPMI8226 multiple myeloma cells and its Melphalan-resistant derivative 8226-LR5.We observed markedly reduced steady-state lev
Linyuan (LY) is a coastal station located down wind of the industrial city of Kaohsiung in southern Taiwan.This station is often affected by severe ozone pollution during sea breeze events.Intensive tethered ozone soundings were per formed at this station during a 4-day ozone episode in November, 2005.Back air trajectories Modern Other were also ca
Mast cells (MCs) are a versatile cell type playing key roles in tissue morphogenesis and host defence against bacteria and parasites.Furthermore, they can enhance immunological danger signals and are implicated in inflammatory disorders like fibrosis.This granulated cell type originates from the myeloid lineage and has similarities to basophilic gr
RNASeq or double-stranded RNA based approaches allowed the reconstruction of a total of 9 full-length or near full-length genomes of the recently discovered grapevine virus T (GVT).In addition, datamining of publicly available grapevine RNASeq transcriptome data allowed the reconstruction of a further 14 GVT genomes from five grapevine sources.Toge
Tandem intracranial aneurysms (TandIAs) are rare but inherently complex, and special technical considerations are required for their surgical management.The present case highlights the key surgical aspects of two carotid-ophthalmic TandIAs ELECTRO HYDRAT incidentally found in a 60-year-old female.Both the aneurysms were superiorly projecting, regul